Enter your vial size and the concentration you want to achieve. The calculator tells you how much BAC water to add.

Common concentrations:

ml of BAC water to add

Formula: ml BAC water = (vial mg × 1,000) ÷ target concentration (mcg/ml)

BAC Water Quick Reference — Common Vial Sizes

Resulting concentrations and per-unit values for the most common vial sizes and BAC water volumes used in peptide research.

Vial Size BAC Water Added Concentration Per 10 Units (0.1 ml) Common For
5 mg1 ml5,000 mcg/ml500 mcgBPC-157 high-dose
5 mg2 ml2,500 mcg/ml250 mcgBPC-157 standard, TB-500
5 mg5 ml1,000 mcg/ml100 mcgIpamorelin, Sermorelin
10 mg2 ml5,000 mcg/ml500 mcgSemaglutide, Tirzepatide
10 mg4 ml2,500 mcg/ml250 mcgTirzepatide low-dose titration
10 mg2 ml5,000 mcg/ml500 mcgRetatrutide
2 mg1 ml2,000 mcg/ml200 mcgCagrilintide, Tesamorelin
2 mg0.5 ml4,000 mcg/ml400 mcgTesamorelin standard

Choosing the Right Amount of BAC Water

The amount of bacteriostatic water you add to a peptide vial directly determines the concentration of your solution — and that concentration determines how precisely you can measure each dose. There is no single "correct" amount; the right volume depends on your dose, your syringe, and your tolerance for measurement error.

Less BAC water = higher concentration. Higher concentration means each syringe marking represents more peptide. This is efficient for storage (less volume per dose) but requires more precision. A 10-unit difference on an insulin syringe at 5,000 mcg/ml represents 500 mcg — a clinically significant amount for potent peptides.

More BAC water = lower concentration. Lower concentration makes each dose easier to measure accurately. If 250 mcg = 0.25 ml (25 units), a 1-unit measurement error is less significant than if 250 mcg = 0.05 ml (5 units). However, more BAC water means larger injection volumes, which can cause more subcutaneous discomfort.

As a general principle: aim for a concentration that places your dose between 10 and 50 units on a 100-unit insulin syringe. This gives enough resolution to measure accurately without requiring uncomfortably large injection volumes. For most peptides, this means 1–3 ml of BAC water per 5 mg vial, and 2–4 ml per 10 mg vial.

Once reconstituted, store your vial upright in the refrigerator at 2–8°C (36–46°F). Bacteriostatic water preserves the solution for 4–6 weeks. Never freeze a reconstituted peptide — ice crystals destroy the peptide structure. Always use a new needle each time you draw from the vial to maintain sterility.

Frequently Asked Questions

For a 5 mg peptide vial, adding 2 ml of bacteriostatic water is the most common choice, giving a concentration of 2,500 mcg/ml. At this concentration, 10 units on a 100-unit insulin syringe = 250 mcg — a standard dose for BPC-157 and many other peptides. You can use 1 ml (5,000 mcg/ml) for higher doses or 5 ml (1,000 mcg/ml) for smaller, more precise doses. Use Mode 1 of the calculator above to find the exact volume for any target concentration.
Not always. Bacteriostatic water (BAC water) is a specific product — sterile water for injection containing 0.9% benzyl alcohol as a preservative. This preservative prevents microbial growth after the vial is first opened, allowing multi-dose use over 4–6 weeks. Some "reconstitution solutions" may be plain sterile water (no preservative, single-use only), sterile saline (0.9% NaCl), or other formulations. For peptide research, bacteriostatic water is strongly preferred for multi-dose vials.
For a 10 mg semaglutide vial, 2 ml of BAC water is the standard starting point, producing a 5 mg/ml (5,000 mcg/ml) concentration. At this concentration: 0.1 ml (10 units) = 500 mcg, a common starting weekly dose. For easier measurement of smaller doses during the initiation phase (250 mcg), add 4 ml instead for a 2,500 mcg/ml concentration where 250 mcg = 0.1 ml exactly.
For a 10 mg tirzepatide vial, 2 ml of BAC water yields 5 mg/ml. The tirzepatide starting dose is 2.5 mg per week, which equals 0.5 ml (50 units) at this concentration — easy to measure accurately. Maintenance doses of 5–15 mg per week translate to 1–3 ml, which may require a larger syringe. Some researchers use 4 ml BAC water for 2.5 mg/ml, making 2.5 mg = 1 ml for even simpler measurement.
For a 10 mg retatrutide vial, 2 ml of BAC water is the most common choice, giving 5,000 mcg/ml. Typical starting doses for retatrutide in research protocols are 2 mg (2,000 mcg) weekly, which equals 0.4 ml (40 units) at this concentration — a practical, easy-to-measure volume. As doses titrate upward to 4–12 mg weekly, volumes scale proportionally. Always verify your calculation with the Mode 2 tool above before each injection.