Cagrilintide Dosage Calculator
Calculate cagrilintide injection volumes. Pre-filled for a 2.4mg vial with 0.5ml BAC water (4,800 mcg/ml). Full dose = 0.5ml = 50 units.
Cagrilintide is a long-acting amylin analogue being studied in combination with semaglutide (as CagriSema) for obesity treatment. Amylin is a hormone co-secreted with insulin that signals satiety and slows gastric emptying — cagrilintide extends this effect with a half-life of approximately 7 days, enabling once-weekly dosing.
For a 2.4mg cagrilintide vial: add 0.5ml of bacteriostatic water → concentration is exactly 4800 mcg/ml. For the standard 2400mcg weekly dose, inject 0.50ml (50 units) on a 100-unit syringe.
Dose Reference Table
Pre-calculated for a 2.4mg vial + 0.5ml BAC water = 4,800 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.
| Dose | Inject Volume (ml) | Syringe Units |
|---|---|---|
| 300mcg | 0.063 ml | 6.3 units |
| 600mcg | 0.125 ml | 12.5 units |
| 1200mcg | 0.250 ml | 25 units |
| 2400mcg (2.4mg) | 0.500 ml | 50 units |
About Cagrilintide
Cagrilintide is a long-acting amylin analogue developed by Novo Nordisk. Amylin is a peptide hormone co-secreted with insulin from pancreatic beta cells in response to meals. It plays a role in satiety signaling, gastric emptying, and glucagon suppression. Cagrilintide is designed for once-weekly subcutaneous administration due to modifications that extend its half-life to approximately 7 days.
Cagrilintide is also being studied in combination with semaglutide ("CagriSema"), which targets both GLP-1 and amylin receptor pathways. Phase 3 results have been announced by the manufacturer; as with all investigational compounds, treat published figures as preliminary until peer-reviewed and regulator-approved.
Cagrilintide is typically supplied in 2.4mg vials, mirroring the maximum weekly dose studied in clinical trials. Reconstituting with 0.5ml of bacteriostatic water gives a concentration of 4,800 mcg/ml. The full 2.4mg dose requires 0.5ml = 50 units on a 100-unit insulin syringe.
As an investigational compound, cagrilintide is studied for its effects on body weight, glycemic control, and metabolic health, typically in combination with GLP-1 receptor agonists.
How this calculator works
Every result comes from the same three formulas used for any lyophilized peptide: concentration (mcg/ml) = vial mg × 1,000 ÷ BAC water ml; injection volume (ml) = desired dose mcg ÷ concentration; syringe units = injection volume ml × 100 on a U-100 syringe.
For the preset Cagrilintide setup on this page: a 2.4mg vial mixed with 0.5ml of bacteriostatic water gives a concentration of 4,800 mcg/ml. A 2,400mcg dose then needs 0.50ml, which is 50 units on a 100-unit insulin syringe.
The full methodology, with worked examples and the assumptions behind each formula, is on the methodology page.
Accuracy & limitations
The arithmetic itself is exact — the same inputs always produce the same output. Real-world accuracy depends on things outside the calculator: actual vial contents can vary slightly from the labeled amount within manufacturing tolerance, the BAC water volume should be measured carefully, and syringe readings are taken at the bottom edge of the plunger. Reconstituted peptides also degrade over time (the common guidance is to use within about 28 days refrigerated), which the math does not model. This tool does arithmetic only — it does not recommend doses, and it is not medical advice.
Last reviewed: September 2026 · Content, formulas and sources checked by Kanika