GHRP-6 is a growth hormone-releasing hexapeptide that stimulates GH release through ghrelin receptor activation. Unlike Ipamorelin, it also increases appetite and raises cortisol and prolactin — effects that limit its use for most researchers. Commonly referenced research doses are 100mcg per injection, 2–3 times daily.

Quick Answer

For a 10mg GHRP-6 vial: add 2ml of bacteriostatic water → concentration is exactly 5000 mcg/ml. A commonly referenced 100mcg research dose = 0.02ml (2 units) on a 100-unit syringe.

Dose Reference Table

Pre-calculated for a 10mg vial + 2ml BAC water = 5,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.

Dose Inject Volume (ml) Syringe Units
50mcg 0.010 ml 1 units
100mcg 0.020 ml 2 units
150mcg 0.030 ml 3 units
200mcg 0.040 ml 4 units
300mcg 0.060 ml 6 units

About GHRP-6

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that stimulates GH secretion from the pituitary gland. It was one of the first GHRPs developed and remains a well-studied reference compound in this class. GHRP-6 acts primarily through the ghrelin receptor (GHSR-1a) to amplify pulsatile GH release.

A notable characteristic of GHRP-6 compared to other GHRPs like Ipamorelin is its strong appetite-stimulating effect. By activating ghrelin receptors — and ghrelin is the body's primary "hunger hormone" — GHRP-6 can significantly increase appetite, which may be either a desired or undesired effect depending on the research context.

GHRP-6 is supplied in 10mg vials. Using 2ml of bacteriostatic water gives 5,000 mcg/ml. Research doses typically range from 100–300mcg per injection, administered 2–3 times daily. GHRP-6 is often combined with a GHRH analogue (CJC-1295, Sermorelin) for a synergistic effect on GH release.

In research, GHRP-6 is typically administered in a fasted state, as elevated blood glucose blunts GH response. The half-life is 15–60 minutes.

How this calculator works

Every result comes from the same three formulas used for any lyophilized peptide: concentration (mcg/ml) = vial mg × 1,000 ÷ BAC water ml; injection volume (ml) = desired dose mcg ÷ concentration; syringe units = injection volume ml × 100 on a U-100 syringe.

For the preset GHRP-6 setup on this page: a 10mg vial mixed with 2ml of bacteriostatic water gives a concentration of 5,000 mcg/ml. A 100mcg dose then needs 0.02ml, which is 2 units on a 100-unit insulin syringe.

The full methodology, with worked examples and the assumptions behind each formula, is on the methodology page.

Accuracy & limitations

The arithmetic itself is exact — the same inputs always produce the same output. Real-world accuracy depends on things outside the calculator: actual vial contents can vary slightly from the labeled amount within manufacturing tolerance, the BAC water volume should be measured carefully, and syringe readings are taken at the bottom edge of the plunger. Reconstituted peptides also degrade over time (the common guidance is to use within about 28 days refrigerated), which the math does not model. This tool does arithmetic only — it does not recommend doses, and it is not medical advice.

Last reviewed: September 2026 · Content, formulas and sources checked by Kanika

Frequently Asked Questions

Common research doses are 100–300mcg per injection, administered 2–3 times daily in a fasted state. For a 10mg vial + 2ml BAC water (5000 mcg/ml), 100mcg = 0.02ml = 2 units.
Yes — GHRP-6 is known for its strong appetite-stimulating effect, more so than Ipamorelin or Hexarelin. This is because it activates ghrelin receptors, and ghrelin is the body's primary hunger hormone.
GHRP-6 stimulates both GH release and hunger (via ghrelin receptors). Ipamorelin is more selective — it stimulates GH release without the hunger-stimulating side effect, making it preferable for researchers who want to avoid appetite increases.
Yes — elevated blood glucose (from eating) blunts GH release. GHRP-6 is typically administered 2+ hours after a meal, or first thing in the morning before eating.
Yes — combining GHRP-6 (a GHRP) with CJC-1295 (a GHRH analogue) is studied for synergistic GH release. The combination provides both GHRH stimulation and GHRP amplification for larger GH pulses.