Epithalon Dosage Calculator
Calculate Epithalon injection volumes. Pre-filled for a 10mg vial with 2ml BAC water (5,000 mcg/ml). Typical 5mg dose = 1ml = 100 units.
Epithalon (Epitalon) is a synthetic tetrapeptide — Ala-Glu-Asp-Gly — derived from the pineal peptide epithalamin. It is studied for its ability to activate telomerase, lengthen telomeres, and regulate melatonin production. Research protocols use it in defined cycles rather than continuous administration.
For a 10mg Epithalon vial: add 2ml of bacteriostatic water → concentration is exactly 5000 mcg/ml. A commonly referenced 5000mcg (5mg) research dose = 1.00ml (100 units) on a 100-unit syringe.
Dose Reference Table
Pre-calculated for a 10mg vial + 2ml BAC water = 5,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.
| Dose | Inject Volume (ml) | Syringe Units |
|---|---|---|
| 1000mcg (1mg) | 0.200 ml | 20 units |
| 2500mcg (2.5mg) | 0.500 ml | 50 units |
| 5000mcg (5mg) | 1.000 ml | 100 units |
| 10000mcg (10mg) | 2.000 ml | 200 units |
About Epithalon
Epithalon (also spelled Epitalon or Epithalamin) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the natural peptide Epithalamin isolated from the bovine pineal gland. It was developed by Russian scientist Vladimir Khavinson at the St. Petersburg Institute of Biogerontology. Epithalon is one of the most studied peptides in the field of geroscience — the science of aging.
Epithalon's primary researched mechanism is the activation of telomerase — the enzyme responsible for lengthening telomeres at the ends of chromosomes. Telomere shortening is a hallmark of cellular aging, and telomerase activation is theorized to slow this process. Animal studies have reported extended lifespan, reduced cancer incidence, and improved markers of biological aging with Epithalon treatment.
Epithalon is typically supplied in 10mg vials. Using 2ml of bacteriostatic water gives 5,000 mcg/ml. Research protocols often use 5–10mg per injection, administered in cycles — a common cycle is 5mg daily for 10–20 days, once or twice yearly. Epithalon is not FDA-approved, and human evidence for anti-aging effects remains limited.
Epithalon also shows melatonin-normalizing properties through pineal gland interactions and has been studied for immune system enhancement, circadian rhythm regulation, and antioxidant effects.
How this calculator works
Every result comes from the same three formulas used for any lyophilized peptide: concentration (mcg/ml) = vial mg × 1,000 ÷ BAC water ml; injection volume (ml) = desired dose mcg ÷ concentration; syringe units = injection volume ml × 100 on a U-100 syringe.
For the preset Epithalon setup on this page: a 10mg vial mixed with 2ml of bacteriostatic water gives a concentration of 5,000 mcg/ml. A 5,000mcg dose then needs 1.00ml, which is 100 units on a 100-unit insulin syringe.
The full methodology, with worked examples and the assumptions behind each formula, is on the methodology page.
Accuracy & limitations
The arithmetic itself is exact — the same inputs always produce the same output. Real-world accuracy depends on things outside the calculator: actual vial contents can vary slightly from the labeled amount within manufacturing tolerance, the BAC water volume should be measured carefully, and syringe readings are taken at the bottom edge of the plunger. Reconstituted peptides also degrade over time (the common guidance is to use within about 28 days refrigerated), which the math does not model. This tool does arithmetic only — it does not recommend doses, and it is not medical advice.
Last reviewed: September 2026 · Content, formulas and sources checked by Kanika