MOTS-C Dosage Calculator
Calculate MOTS-C injection volumes. Pre-filled for a 10mg vial with 2ml BAC water (5,000 mcg/ml). Typical 5mg dose = 1ml = 100 units.
Dose Reference Table
Pre-calculated for a 10mg vial + 2ml BAC water = 5,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.
| Dose | Inject Volume (ml) | Syringe Units |
|---|---|---|
| 1000mcg (1mg) | 0.200 ml | 20 units |
| 2500mcg (2.5mg) | 0.500 ml | 50 units |
| 5000mcg (5mg) | 1.000 ml | 100 units |
| 7500mcg (7.5mg) | 1.500 ml | 150 units |
| 10000mcg (10mg) | 2.000 ml | 200 units |
About MOTS-C
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a recently discovered mitochondria-derived peptide (MDP) encoded in the mitochondrial genome. It was first characterized in 2015 by researchers at the University of Southern California. MOTS-C represents a new class of peptide signals that coordinate nuclear gene expression from within the mitochondria.
Research on MOTS-C has explored its role in metabolic regulation, insulin sensitivity, exercise performance, and aging. It appears to work by translocating from mitochondria to the cell nucleus, where it regulates genes involved in metabolism, antioxidant defense, and stress response. Studies in animal models have shown improvements in insulin sensitivity, reductions in diet-induced obesity, and enhanced endurance exercise performance.
MOTS-C is typically supplied in 10mg vials. Using 2ml of bacteriostatic water yields 5,000 mcg/ml. Research doses have ranged from 1mg to 10mg per injection. Given the novelty of this peptide, optimal dosing protocols are still being established in the research literature.