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SS-31 Dosage Calculator

Calculate SS-31 (Elamipretide) injection volumes. Pre-filled for a 50mg vial with 5ml BAC water (10,000 mcg/ml).

Dose Reference Table

Pre-calculated for a 50mg vial + 5ml BAC water = 10,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.

Dose Inject Volume (ml) Syringe Units
1000mcg (1mg) 0.100 ml 10 units
2000mcg (2mg) 0.200 ml 20 units
3000mcg (3mg) 0.300 ml 30 units
5000mcg (5mg) 0.500 ml 50 units
10000mcg (10mg) 1.000 ml 100 units

About SS-31

SS-31 (Szeto-Schiller peptide 31), also known as Elamipretide or MTP-131, is a cell-permeable tetrapeptide that specifically targets cardiolipin — a phospholipid found exclusively in the inner mitochondrial membrane. By interacting with cardiolipin, SS-31 helps maintain cristae structure, supports electron transport chain function, and reduces reactive oxygen species (ROS) production.

SS-31 has been studied for its potential benefits in cardiac function, skeletal muscle performance, kidney protection, and neurological conditions. It has been investigated in clinical trials for heart failure with preserved ejection fraction (HFpEF), Barth syndrome, and other mitochondria-related conditions.

SS-31 is supplied in larger vials (commonly 50mg) because research doses are in the milligram range. Using 5ml of bacteriostatic water gives a concentration of 10,000 mcg/ml (10 mg/ml). A 3mg dose requires 0.3ml — 30 units on a 100-unit insulin syringe.

SS-31 is administered via subcutaneous injection. Research protocols vary widely from daily to several times weekly depending on the study objective.

Frequently Asked Questions

Research doses of SS-31 vary by study, ranging from 1–10mg per day. Common research protocols use 3–5mg per injection. For a 50mg vial + 5ml BAC water (10,000 mcg/ml), 3mg = 0.3ml = 30 units.
SS-31 targets cardiolipin in the inner mitochondrial membrane, supporting electron transport chain efficiency, reducing oxidative stress, and potentially improving mitochondrial function in aged or damaged cells.
Add 5ml of bacteriostatic water to a 50mg SS-31 vial for a concentration of 10,000 mcg/ml (10 mg/ml). Inject BAC water slowly along the glass wall and gently swirl until dissolved. Store at 2–8°C.
Clinical trials have studied SS-31 for heart failure with preserved ejection fraction (HFpEF). Preliminary results suggest improvements in exercise capacity and mitochondrial function in cardiac tissue.
When reconstituted with bacteriostatic water and stored at 2–8°C, SS-31 is typically stable for 28–30 days. Keep refrigerated and protected from light.
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