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Melanotan II Dosage Calculator

Calculate Melanotan II injection volumes. Pre-filled for a 10mg vial with 2ml BAC water (5,000 mcg/ml). Typical 500mcg dose = 0.1ml = 10 units.

Melanotan 2 (MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that activates melanocortin receptors to stimulate eumelanin production — the pigment responsible for skin darkening. Research has also documented effects on libido through MC4R receptor activation. It is unrelated to melatonin.

Quick Answer

For a 10mg Melanotan 2 vial: add 2ml of bacteriostatic water → concentration is exactly 5000 mcg/ml. For a standard 500mcg maintenance dose, inject 0.10ml (10 units) on a 100-unit syringe.

Dose Reference Table

Pre-calculated for a 10mg vial + 2ml BAC water = 5,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.

Dose Inject Volume (ml) Syringe Units
250mcg 0.050 ml 5 units
500mcg 0.100 ml 10 units
750mcg 0.150 ml 15 units
1000mcg 0.200 ml 20 units
1500mcg 0.300 ml 30 units

About Melanotan II

Melanotan II is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH), a melanocortin peptide. It was originally developed at the University of Arizona for potential use as a sunless tanning agent and as a treatment for sexual dysfunction. PT-141 was later derived from Melanotan II by removing the cyclic lactam ring.

Melanotan II activates melanocortin receptors (MC1R, MC3R, MC4R, and MC5R), which drives melanin production (tanning effect via MC1R), reduces appetite, and influences sexual arousal (via MC3R/MC4R). This multi-receptor activity gives it a broader profile than PT-141.

Melanotan II is supplied in 10mg vials. Using 2ml of bacteriostatic water yields 5,000 mcg/ml. Common research doses start low (250–500mcg) to assess tolerability, with some researchers escalating higher. It is administered via subcutaneous injection.

Note: Melanotan II is a research compound and is not approved for human use by any regulatory body. Researchers should be aware of potential side effects including nausea, spontaneous erections, facial flushing, and darkening of existing moles.

Frequently Asked Questions

Research protocols typically start with low doses of 250–500mcg to assess tolerability, sometimes increasing to 1mg. For a 10mg vial + 2ml BAC water (5000 mcg/ml), 500mcg = 0.1ml = 10 units.
Add 2ml of bacteriostatic water to a 10mg Melanotan II vial. Inject slowly along the glass wall, gently swirl until dissolved. Store at 2–8°C. The solution should be clear and colorless.
A 10mg vial at 500mcg/dose provides approximately 20 doses. Reconstituted with BAC water and refrigerated, the solution is typically stable for 28–30 days.
In research, skin darkening effects typically develop over 2–4 weeks with regular dosing and UV exposure. Individual results vary significantly based on natural skin tone and genetics.
PT-141 was derived from Melanotan II. PT-141 primarily targets MC3R/MC4R for sexual effects with reduced tanning. Melanotan II targets all melanocortin receptors more broadly, including MC1R for melanin/tanning.
PT-141 Dosage PT-141 dosage calculator. Reconstitution Calculator Universal calculator. BAC Water Calculator Calculate BAC water. Peptide Dosage Chart Reference chart.