Dose Reference Table

Pre-calculated for a 10mg vial + 2ml BAC water = 5,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.

Dose Inject Volume (ml) Syringe Units
500mcg 0.100 ml 10 units
750mcg 0.150 ml 15 units
1000mcg 0.200 ml 20 units
1500mcg 0.300 ml 30 units
2000mcg 0.400 ml 40 units

About PT-141

PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist derived from Melanotan II. Unlike Melanotan II which primarily targets MC1R for tanning and weight effects, PT-141 preferentially targets MC3R and MC4R receptors in the brain, which are involved in sexual arousal in both men and women.

PT-141 is FDA-approved under the brand name Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women. In research settings, it has been studied for both male and female sexual dysfunction and arousal enhancement.

PT-141 is typically supplied in 10mg vials. Reconstituting with 2ml of bacteriostatic water gives a concentration of 5,000 mcg/ml. The typical research dose is 0.75–2mg (750–2000mcg), administered 45–90 minutes before anticipated activity via subcutaneous injection.

PT-141 has a half-life of approximately 12 hours. It is generally not recommended for daily use. Common side effects in research include transient nausea and flushing.

Frequently Asked Questions

Common research doses range from 0.75mg to 2mg (750–2000mcg). For a 10mg vial + 2ml BAC water (5000 mcg/ml), 1mg = 0.2ml = 20 units.
PT-141 is typically administered 45–90 minutes before anticipated activity via subcutaneous injection. Effects can last 6–12 hours given its half-life.
Add 2ml of bacteriostatic water to a 10mg PT-141 vial for a 5000 mcg/ml concentration. Inject BAC water slowly along the glass wall, swirl gently, and store at 2–8°C.
PT-141 has a half-life of approximately 12 hours. Effects are typically felt within 1–2 hours of injection and can persist for several hours.
With 10mg + 2ml BAC water (5000 mcg/ml): 1mg (1000mcg) = 0.2ml = 20 units on a 100-unit insulin syringe.