Sermorelin Dosage Calculator
Calculate sermorelin injection volumes. Pre-filled for a 6mg vial with 3ml BAC water (2,000 mcg/ml). Typical 200mcg dose = 0.1ml = 10 units.
Sermorelin is a synthetic analogue of the first 29 amino acids of endogenous GHRH (growth hormone-releasing hormone). It stimulates the pituitary to produce and secrete its own growth hormone, making it distinct from synthetic GH — the response is pulsatile and physiologically regulated rather than supraphysiological.
For a 6mg Sermorelin vial: add 3ml of bacteriostatic water → concentration is exactly 2000 mcg/ml. A commonly referenced 200mcg research dose = 0.10ml (10 units) on a 100-unit syringe.
Dose Reference Table
Pre-calculated for a 6mg vial + 3ml BAC water = 2,000 mcg/ml concentration. Using a 100-unit (1ml) insulin syringe.
| Dose | Inject Volume (ml) | Syringe Units |
|---|---|---|
| 100mcg | 0.050 ml | 5 units |
| 150mcg | 0.075 ml | 7.5 units |
| 200mcg | 0.100 ml | 10 units |
| 300mcg | 0.150 ml | 15 units |
| 500mcg | 0.250 ml | 25 units |
| 1000mcg | 0.500 ml | 50 units |
About Sermorelin
Sermorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), consisting of the first 29 amino acids of endogenous GHRH. It stimulates the pituitary gland to produce and secrete natural growth hormone, making it distinct from exogenous GH administration.
Sermorelin was historically FDA-approved under the brand name Geref for treating GH deficiency in children, though the branded product was later discontinued in the US market. It has since been studied in adult applications for age-related GH decline, body composition, sleep quality, and recovery. Because it works through the pituitary's own regulatory mechanisms rather than delivering exogenous GH, it preserves the natural feedback loop.
Sermorelin is typically supplied in 6mg vials. Reconstituting with 3ml of bacteriostatic water gives 2,000 mcg/ml — the concentration behind the commonly referenced 200mcg dose (0.1ml = 10 units). Due to its very short half-life of 10–20 minutes, sermorelin has typically been administered as a single bedtime injection to align with the body's natural nighttime GH pulse.
Sermorelin research explores its use in male and female adults for anti-aging, fat loss, lean muscle maintenance, sleep improvement, and recovery enhancement.
How this calculator works
Every result comes from the same three formulas used for any lyophilized peptide: concentration (mcg/ml) = vial mg × 1,000 ÷ BAC water ml; injection volume (ml) = desired dose mcg ÷ concentration; syringe units = injection volume ml × 100 on a U-100 syringe.
For the preset Sermorelin setup on this page: a 6mg vial mixed with 3ml of bacteriostatic water gives a concentration of 2,000 mcg/ml. A 200mcg dose then needs 0.10ml, which is 10 units on a 100-unit insulin syringe.
The full methodology, with worked examples and the assumptions behind each formula, is on the methodology page.
Accuracy & limitations
The arithmetic itself is exact — the same inputs always produce the same output. Real-world accuracy depends on things outside the calculator: actual vial contents can vary slightly from the labeled amount within manufacturing tolerance, the BAC water volume should be measured carefully, and syringe readings are taken at the bottom edge of the plunger. Reconstituted peptides also degrade over time (the common guidance is to use within about 28 days refrigerated), which the math does not model. This tool does arithmetic only — it does not recommend doses, and it is not medical advice.
Last reviewed: September 2026 · Content, formulas and sources checked by Kanika